From Wikipedia, the free encyclopedia
Jump to: navigation, search
Systematic (IUPAC) name
Clinical data
MedlinePlus a682065
Legal status
Routes Oral
Pharmacokinetic data
Bioavailability High
Protein binding 96%
Metabolism Mostly hepatic (CYP-mediated), also renal
Half-life 1 to 4 hours
CAS number 1808-12-4 YesY 1808-12-4
ATC code R06AA01
PubChem CID 2444
DrugBank DB01237
ChemSpider 2350 YesY
UNII 202J683U97 YesY
ChEBI CHEBI:59177 YesY
Chemical data
Formula C17H20BrNO 
Molecular mass 334.251 g/mol
 N (what is this?)  (verify)

Bromazine (trade names Ambrodyl, Ambrodil and others), also known as bromodiphenhydramine, is an antihistamine and anticholinergic.[1] It is a halogenated form of diphenhydramine and in many respects is somewhat stronger than the parent compound. The other three halogenated diphenhydramine derivatives are used in research and chlorodiphenhydramine is also marketed with iododiphenhydramine being a much less common pharmaceutical.


  1. ^ MacLaren, W. R.; Bruff, W. C.; Eisenberg, B. C.; Weiner, H.; Martin, W. H. (1955). "A clinical comparison of carbinoxamine maleate, tripelennamine hydrochloride, and bromodiphenhydramine hydrochloride in treating allergic symptoms". Annals of allergy 13 (3): 307–312. PMID 14377226.  edit