|Jmol-3D images||Image 1|
|Molar mass||698.01 g mol−1|
|Acidity (pKa)||4.90 |
| (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C or 77 °F, 100 kPa)
|Bromocresol green (pH indicator)|
|below pH 3.8||above pH 5.4|
Bromocresol Green (BCG) is a dye of the triphenylmethane family (triarylmethane dyes), which is used as a pH indicator and as a tracking dye for DNA agarose gel electrophoresis. It can be used in its free acid form (light brown solid), or as a sodium salt (dark green solid). It is also an inhibitor of the prostaglandin E2 transport protein.
Ethanol solution (0.04 wt.%) of Bromocresol Green has been proposed for TLC staining and is suitable for visualisation of the compounds with functional groups whose pKa is below 5.0 (carboxylic acids, sulfonic acids etc.). These appear as yellow spots on light or dark blue background; no heating is necessary. Bromophenol Blue solution can be used for the same purpose.
The compound is synthesized by bromination of Cresol Purple (m-cresolsulfonphthalein).
- Kolthoff, I.M. Treatise on Analytical Chemistry, New York, Interscience Encyclopedia, Inc., 1959.
- D. Diamond, K.T. Lau, S. Brady, J. Cleary, Talanta, 2008, 75, 606-612