Bucetin

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Bucetin
Bucetin.svg
Systematic (IUPAC) name
N-(4-Ethoxyphenyl)-3-hydroxybutanamide
Clinical data
Legal status ?
Identifiers
ATC code N02BE04
PubChem CID 14130
ChemSpider 13507
ChEMBL CHEMBL1697856
Chemical data
Formula C12H17NO3 
Mol. mass 223.268 g/mol

Bucetin is a pharmaceutical drug that acts as an analgesic and antipyretic.[1] Chemically, it is similar to phenacetin with which it shares the risk of carcinogenesis.[2] Bucetin was withdrawn from use in 1986 due to renal toxicity.[3]

See also[edit]

References[edit]

  1. ^ "WHOCC - ATC/DDD Index". WHO Collaborating Centre for Drug Statistics Methodology. December 19, 2013. 
  2. ^ Togei, K; Sano, N; Maeda, T; Shibata, M; Otsuka, H (1987). "Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice". Journal of the National Cancer Institute 79 (5): 1151–8. doi:10.1093/jnci/79.5.1151. PMID 3479641. Closed access
  3. ^ Fung, M.; Thornton, A.; Mybeck, K.; Wu, J. H.-h.; Hornbuckle, K.; Muniz, E. (2001). "Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999". Drug Information Journal 35: 293–317. doi:10.1177/009286150103500134. Closed access