The game required Bucky to rescue each of his crew members (except Bruiser, who is not featured in the game) on a series of planets. As each character was rescued, the player gained the ability to switch between them and Bucky on the fly to deal with different problems. Immediately after regaining his entire crew, they are once again captured and imprisoned on the Toad mother ship. Bucky and Blinky, sharing the same cell, break out and must rescue the remaining members. Afterwards, you continue through the monstrous ship.
An arcade game by Konami was also released which allowed players to control Bucky, Jenny, Willie, Deadeye, or Blinky in a format similar to the arcade games based on Teenage Mutant Ninja Turtles or The Simpsons. Perhaps to satisfy fans when a second season was not released, the plot of the arcade game allowed players to achieve final victory over the toads by releasing an energy called the Interplanetary Life Force contained within KOMPLEX. This last hurrah to the series also featured the original voice cast.