Bucladesine

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Bucladesine
Bucladesine.svg
Systematic (IUPAC) name
sodium (3aR,4R,6R,6aR)-4-(6-butanamido-9H-purin-9-yl)-6-[(butanoyloxy)methyl]-2-oxo-tetrahydro-2H-1,3,5,2λ5-furo[3,4-d][1,3,2]dioxaphosphol-2-olate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status ?
Identifiers
CAS number 362-74-3 YesY
ATC code C01CE04
PubChem CID 28177
ChemSpider 9306 YesY
UNII 63X7MBT2LQ YesY
ChEBI CHEBI:50095 YesY
ChEMBL CHEMBL485980 YesY
Synonyms • Dibutyryl cyclic adenosine monophosphate
• (N6,2'-O-dibutyryl)-adenosine-3',5'-mono-phosphate
• Dibutyryl cAMP
• DcAMP
• DBcAMP
Chemical data
Formula C18H23N5NaO8P 
Mol. mass 491.368 g/mol
 YesY (what is this?)  (verify)

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor.

Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.

The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.

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