Bullatacin

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(+)-Bullatacin
Bullatacin.svg
Identifiers
CAS number 123123-32-0 N=
PubChem 114749
ChemSpider 9300122 YesY
Jmol-3D images Image 1
Properties
Molecular formula C37H66O7
Molar mass 622.92 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N
Infobox references

Bullatacin is a bis(tetrahydrofuranoid) fatty acid lactone found in some fruits from Annonaceae family. It is a member of the class of compounds known as acetogenins.[1][2][3]

References[edit]

  1. ^ H. Naito; E. Kawahara; K. Maruta; M. Maeda; S. Sasaki (1995). "The First Total Synthesis of (+)-Bullatacin, a Potent Antitumor Annonaceous Acetogenin, and (+)-(15,24)-bis-epi-Bullatacin". Journal of Organic Chemistry 60 (14): 4419–4427. doi:10.1021/jo00119a019. 
  2. ^ H.-W. Chih; H.-F. Chiu; K.-S. Tang; F.-R. Chang; Y.-C. Wu (2001). "Bullatacin, a potent antitumor annonaceous acetogenin, inhibits proliferation of human hepatocarcinoma cell line 2.2.15 by apoptosis induction". Life Sciences 69 (11): 1321–1331. doi:10.1016/S0024-3205(01)01209-7. PMID 11521756. 
  3. ^ Y.-H. Hui; J. K. Rupprecht; Y. M. Liu; J. E. Anderson; D. L. Smith; C.-J. Chang; J. L. McLaughlin (1989). "Bullatacin and Bullatacinone: Two Highly Potent Bioactive Acetogenins from Annona bullata". Journal of Natural Products 52 (3): 463–477. doi:10.1021/np50063a002. PMID 2778448.