|Molar mass||222.305 g/mol|
|Melting point||215 °C (419 °F; 488 K)|
|Boiling point||382.3 °C (720.1 °F; 655.5 K)|
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
|what is: / ?)(|
Buthionine sulfoximine is a sulfoximine which reduces levels of glutathione and is being investigated as an adjunct with chemotherapy in the treatment of cancer. The compound inhibits gamma-glutamylcysteine synthetase, the enzyme required in the first step of glutathione synthesis. Buthionine sulfoximine may also be used to increase the sensitivity of parasites to oxidative antiparasitic drugs.
- Defty, CL; Marsden, JR (2012). "Melphalan in regional chemotherapy for locally recurrent metastatic melanoma.". Current topics in medicinal chemistry 12 (1): 53–60. PMID 22196271.
- "Definition of buthionine sulfoximine - National Cancer Institute Drug Dictionary".
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