C11orf30

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Chromosome 11 open reading frame 30
Protein C11orf30 PDB 1utu.png
PDB rendering based on 1utu.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols C11orf30 ; EMSY
External IDs OMIM608574 MGI1924203 HomoloGene32465 GeneCards: C11orf30 Gene
RNA expression pattern
PBB GE C11orf30 219012 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 56946 233545
Ensembl ENSG00000158636 ENSMUSG00000035401
UniProt Q7Z589 Q8BMB0
RefSeq (mRNA) NM_020193 NM_172280
RefSeq (protein) NP_064578 NP_758484
Location (UCSC) Chr 11:
76.16 – 76.26 Mb
Chr 7:
98.59 – 98.66 Mb
PubMed search [1] [2]

Protein EMSY is a protein that in humans is encoded by the C11orf30 gene.[1]


Interactions[edit]

C11orf30 has been shown to interact with ZMYND11,[2] BRCA2[2] and CBX1.[2]

References[edit]

  1. ^ "Entrez Gene: C11orf30 chromosome 11 open reading frame 30". 
  2. ^ a b c Hughes-Davies, Luke; Huntsman David, Ruas Margarida, Fuks Francois, Bye Jacqueline, Chin Suet-Feung, Milner Jonathon, Brown Lindsay A, Hsu Forrest, Gilks Blake, Nielsen Torsten, Schulzer Michael, Chia Stephen, Ragaz Joseph, Cahn Anthony, Linger Lori, Ozdag Hilal, Cattaneo Elena, Jordanova E S, Schuuring Edward, Yu David S, Venkitaraman Ashok, Ponder Bruce, Doherty Aidan, Aparicio Samuel, Bentley David, Theillet Charles, Ponting Chris P, Caldas Carlos, Kouzarides Tony (Nov 2003). "EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer". Cell (United States) 115 (5): 523–35. doi:10.1016/S0092-8674(03)00930-9. ISSN 0092-8674. PMID 14651845. 

Further reading[edit]