From Wikipedia, the free encyclopedia
Jump to: navigation, search
Progesterone immunomodulatory binding factor 1
Symbols PIBF1 ; C13orf24; CEP90; PIBF
External IDs OMIM607532 MGI1261910 HomoloGene4628 GeneCards: PIBF1 Gene
RNA expression pattern
PBB GE C13orf24 213239 at tn.png
More reference expression data
Species Human Mouse
Entrez 10464 52023
Ensembl ENSG00000083535 ENSMUSG00000022064
UniProt Q8WXW3 E9Q6K3
RefSeq (mRNA) NM_006346 NM_029320
RefSeq (protein) NP_006337 NP_083596
Location (UCSC) Chr 13:
73.36 – 73.59 Mb
Chr 14:
99.1 – 99.25 Mb
PubMed search [1] [2]

Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene.[1][2] It has been shown to localize to the centrosome[3] and has also been named CEP90.[4]


  1. ^ Rozenblum E, Vahteristo P, Sandberg T, Bergthorsson JT, Syrjakoski K, Weaver D, Haraldsson K, Johannsdottir HK, Vehmanen P, Nigam S, Golberger N, Robbins C, Pak E, Dutra A, Gillander E, Stephan DA, Bailey-Wilson J, Juo SH, Kainu T, Arason A, Barkardottir RB, Nevanlinna H, Borg A, Kallioniemi OP (Apr 2002). "A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes". Hum Genet 110 (2): 111–21. doi:10.1007/s00439-001-0646-6. PMID 11935316. 
  2. ^ "Entrez Gene: C13orf24 chromosome 13 open reading frame 24". 
  3. ^ Lachmann M, Gelbmann D, Kálmán E et al. (2004). "PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome.". Int. J. Cancer 112 (1): 51–60. doi:10.1002/ijc.20326. PMID 15305375. 
  4. ^ Kim, K.; Rhee, K. (2011). "The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole". Journal of Cell Science 124 (Pt 3): 338–347. doi:10.1242/jcs.078329. PMID 21224392.  edit

Further reading[edit]