C2C12

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C2C12 is a mouse myoblast cell line. C2C12 cells were originally obtained by Yaffe and Saxel through serial passage of myoblasts cultured from the thigh muscle of C3H mice after a crush injury. These cells are capable of differentiation. C2C12 cells are a useful tool to study the differentiation of myoblast and osteoblast, to express various proteins, and to explore mechanistic pathways.[1]

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