C3a receptor

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Complement component 3a receptor 1
Identifiers
Symbols C3AR1 ; AZ3B; C3AR; HNFAG09
External IDs OMIM605246 MGI1097680 HomoloGene2992 IUPHAR: C3a receptor ChEMBL: 4761 GeneCards: C3AR1 Gene
RNA expression pattern
PBB GE C3AR1 209906 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 719 12267
Ensembl ENSG00000171860 ENSMUSG00000040552
UniProt Q16581 O09047
RefSeq (mRNA) NM_004054 NM_009779
RefSeq (protein) NP_004045 NP_033909
Location (UCSC) Chr 12:
8.21 – 8.22 Mb
Chr 6:
122.85 – 122.86 Mb
PubMed search [1] [2]

The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system.[1][2]

Although its official name implies it only binds C3a, it also binds C4a.[3]

References[edit]

  1. ^ Roglic A, Prossnitz ER, Cavanagh SL, Pan Z, Zou A, Ye RD (1996). "cDNA cloning of a novel G protein-coupled receptor with a large extracellular loop structure". Biochim. Biophys. Acta 1305 (1–2): 39–43. doi:10.1016/0167-4781(95)00209-x. PMID 8605247. 
  2. ^ Ali H, Panettieri RA (2005). "Anaphylatoxin C3a receptors in asthma". Respir. Res. 6: 19. doi:10.1186/1465-9921-6-19. PMC 551592. PMID 15723703. 
  3. ^ Klos A, Wende E, Wareham KJ, Monk PN. (2013). "International Union of Pharmacology. LXXXVII. Complement peptide C5a, C4a, and C3a receptors". Pharmacol. Rev. 65 (1): 500–43. doi:10.1124/pr.111.005223. PMID 23383423. 

Further reading[edit]

External links[edit]