CA10

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Carbonic anhydrase X
Identifiers
Symbols CA10 ; CA-RPX; CARPX; HUCEP-15
External IDs OMIM604642 MGI1919855 HomoloGene23201 ChEMBL: 4645 GeneCards: CA10 Gene
RNA expression pattern
PBB GE CA10 220889 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 56934 72605
Ensembl ENSG00000154975 ENSMUSG00000056158
UniProt Q9NS85 P61215
RefSeq (mRNA) NM_001082533 NM_028296
RefSeq (protein) NP_001076002 NP_082572
Location (UCSC) Chr 17:
49.71 – 50.24 Mb
Chr 11:
93.1 – 93.6 Mb
PubMed search [1] [2]

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.[1][2][3]

This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.[3]

References[edit]

  1. ^ Hewett-Emmett D, Tashian RE (Aug 1996). "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families". Mol Phylogenet Evol 5 (1): 50–77. doi:10.1006/mpev.1996.0006. PMID 8673298. 
  2. ^ Kleiderlein JJ, Nisson PE, Jessee J, Li WB, Becker KG, Derby ML, Ross CA, Margolis RL (Feb 1999). "CCG repeats in cDNAs from human brain". Hum Genet 103 (6): 666–73. doi:10.1007/s004390050889. PMID 9921901. 
  3. ^ a b "Entrez Gene: CA10 carbonic anhydrase X". 

Further reading[edit]