CACNA1G

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Calcium channel, voltage-dependent, T type, alpha 1G subunit
Identifiers
Symbols CACNA1G ; Ca(V)T.1; Cav3.1; NBR13
External IDs OMIM604065 MGI1201678 HomoloGene22544 IUPHAR: Cav3.1 ChEMBL: 4641 GeneCards: CACNA1G Gene
Orthologs
Species Human Mouse
Entrez 8913 12291
Ensembl ENSG00000006283 ENSMUSG00000020866
UniProt O43497 Q5SUG1
RefSeq (mRNA) NM_001256324 NM_001112813
RefSeq (protein) NP_001243253 NP_001106284
Location (UCSC) Chr 17:
48.64 – 48.7 Mb
Chr 11:
94.41 – 94.47 Mb
PubMed search [1] [2]

Calcium channel, voltage-dependent, T type, alpha 1G subunit, also known as CACNA1G or Cav3.1 is a protein which in humans is encoded by the CACNA1G gene.[1][2][3]

Function[edit]

Voltage-dependent calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance. Low-voltage-activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.[1]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to link to respective Wikipedia articles. [§ 1]

[[File:
NicotineActivityonChromaffinCells_WP1603 Go to article go to article Go to article Go to article Go to article Go to article go to article go to article Go to article Go to article go to article Go to article Go to article
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
NicotineActivityonChromaffinCells_WP1603 Go to article go to article Go to article Go to article Go to article Go to article go to article go to article Go to article Go to article go to article Go to article Go to article
|{{{bSize}}}px|class=noresize]]
Nicotine Activity on Chromaffin Cells edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "NicotineActivityonChromaffinCells_WP1603". 

See also[edit]

References[edit]

  1. ^ a b "Entrez Gene: CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit". 
  2. ^ Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH (February 1998). "Molecular characterization of a neuronal low-voltage-activated T-type calcium channel". Nature 391 (6670): 896–900. doi:10.1038/36110. PMID 9495342. 
  3. ^ Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J (December 2005). "International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels". Pharmacol. Rev. 57 (4): 411–25. doi:10.1124/pr.57.4.5. PMID 16382099. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.