CALN1

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Calneuron 1
Identifiers
Symbols CALN1 ; CABP8
External IDs OMIM607176 MGI2155987 HomoloGene10966 GeneCards: CALN1 Gene
Orthologs
Species Human Mouse
Entrez 83698 140904
Ensembl ENSG00000183166 ENSMUSG00000060371
UniProt Q9BXU9 Q9JJG7
RefSeq (mRNA) NM_001017440 NM_021371
RefSeq (protein) NP_001017440 NP_067346
Location (UCSC) Chr 7:
71.24 – 71.91 Mb
Chr 5:
130.37 – 130.84 Mb
PubMed search [1] [2]

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.[1][2] Alternative splicing results in multiple transcript variants.[2]

Function[edit]

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites.[3]

References[edit]

  1. ^ Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Mol Genet Metab 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509. 
  2. ^ a b "Entrez Gene: CALN1 calneuron 1". 
  3. ^ McCue HV, Haynes JW, Burgoyne RD. (2010). "The diversity of calcium sensor proteins in the regulation of neuronal function.". Cold Spring Harb Perspect Biol. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMID 20668007. 


Further reading[edit]