CAR-302,196

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CAR-302,196
CAR-302,196 structure.png
Systematic (IUPAC) name
(1-methylpiperidin-4-yl) 2-cyclopentyl-2-hydroxypent-3-ynoate
Clinical data
Legal status
?
Identifiers
CAS number 53034-67-6
ATC code ?
PubChem CID 198289
ChemSpider 171624
Chemical data
Formula C16H25NO3 
Mol. mass 279.374 g/mol
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CAR-302,196 (also known as PCMG or just by its code number 302196) is a moderately potent and relatively short lasting anticholinergic deliriant drug, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.

CAR-302,196 was found to be only around 1/4 the potency of QNB, but its onset of action was much faster at only a few minutes, and the duration far shorter at only 2-3 hours. A fast-acting and short-lasting anticholinergic drug was felt to be more desirable for some applications.[1][2]

See also[edit]

References[edit]

  1. ^ Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents, Volume 1 (1982). Commission on Life Sciences. The National Academies Press. pp206-207.
  2. ^ Ketchum JS. Chemical Warfare Secrets Almost Forgotton. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks Inc 2006. ISBN 978-1-4243-0080-8