CCNI (gene)

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Cyclin I
Identifiers
Symbols CCNI ; CYC1; CYI
External IDs MGI1341077 HomoloGene4979 GeneCards: CCNI Gene
RNA expression pattern
PBB GE CCNI 208655 at tn.png
PBB GE CCNI 208656 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10983 12453
Ensembl ENSG00000118816 ENSMUSG00000063015
UniProt Q14094 Q9Z2V9
RefSeq (mRNA) NM_006835 NM_017367
RefSeq (protein) NP_006826 NP_059063
Location (UCSC) Chr 4:
77.97 – 78 Mb
Chr 5:
93.18 – 93.21 Mb
PubMed search [1] [2]

Cyclin-I is a protein that in humans is encoded by the CCNI gene.[1][2]

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined.[2]

References[edit]

  1. ^ Nakamura T, Sanokawa R, Sasaki YF, Ayusawa D, Oishi M, Mori N (Jan 1996). "Cyclin I: a new cyclin encoded by a gene isolated from human brain". Exp Cell Res 221 (2): 534–42. doi:10.1006/excr.1995.1406. PMID 7493655. 
  2. ^ a b "Entrez Gene: CCNI cyclin I". 

Further reading[edit]