CD200

From Wikipedia, the free encyclopedia
Jump to: navigation, search
For the vehicle, see Honda CD200 RoadMaster.
CD200 molecule
Identifiers
Symbols CD200 ; MOX1; MOX2; MRC; OX-2
External IDs OMIM155970 MGI1196990 HomoloGene4344 GeneCards: CD200 Gene
RNA expression pattern
PBB GE CD200 209582 s at tn.png
PBB GE CD200 209583 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4345 17470
Ensembl ENSG00000091972 ENSMUSG00000022661
UniProt P41217 O54901
RefSeq (mRNA) NM_001004196 NM_010818
RefSeq (protein) NP_001004196 NP_034948
Location (UCSC) Chr 3:
112.05 – 112.08 Mb
Chr 16:
45.38 – 45.41 Mb
PubMed search [1] [2]

OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200)[1] is a human protein encoded by the CD200 gene.[2]

The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.[2]

See also[edit]

References[edit]

  1. ^ "P41217 (OX2G_HUMAN)". Uniprot. Retrieved 16 May 2013. 
  2. ^ a b "Entrez Gene: CD200 CD200 molecule". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.