CD24

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CD24 molecule
Identifiers
Symbols CD24 ; CD24A
External IDs OMIM600074 HomoloGene122183 GeneCards: CD24 Gene
Orthologs
Species Human Mouse
Entrez 100133941 n/a
Ensembl ENSG00000185275 n/a
UniProt P25063 n/a
RefSeq (mRNA) NM_013230 n/a
RefSeq (protein) NP_037362 n/a
Location (UCSC) Chr na:
19.61 – 19.61 Mb
n/a
PubMed search [1] n/a

Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a protein that in humans is encoded by the CD24 gene.[1] CD24 is a cell adhesion molecule.

Function[edit]

CD24 is a glycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and in many B cells. The encoded protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. An alignment of this gene's sequence finds genomic locations with similarity on chromosomes 3p26, 15q21, 15q22, 20q11.2 and Yq11.1. Whether transcription, and corresponding translation, occurs at each of these other genomic locations needs to be experimentally determined (source: NCBI).

References[edit]

  1. ^ Hough MR, Rosten PM, Sexton TL, Kay R, Humphries RK (July 1994). "Mapping of CD24 and homologous sequences to multiple chromosomal loci". Genomics 22 (1): 154–61. doi:10.1006/geno.1994.1356. PMID 7959762. 

Further reading[edit]

External links[edit]