CDCA7L

CDCA7L
Identifiers
Aliases	CDCA7L, JPO2, R1, RAM2, cell division cycle associated 7 like
External IDs	OMIM: 609685 MGI: 2384982 HomoloGene: 10285 GeneCards: CDCA7L
Gene location (Human)
Chr.	Chromosome 7 (human)
End	21,945,903 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	117,842,441 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; pancreatic ductal cell; ; right uterine tube; ; bone marrow; ; ganglionic eminence; ; palpebral conjunctiva; ; parietal pleura; ; bone marrow cells; ; parotid gland; ; endothelial cell;
	Top expressed in
	Bowman's capsule; ; primitive streak; ; secondary oocyte; ; medullary collecting duct; ; somite; ; otic placode; ; submandibular gland; ; ureter; ; Paneth cell; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	nucleolus; nucleus; fibrillar center; cytoplasm; cytosol;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of cell population proliferation;
	Sources:Amigo / QuickGO
Orthologs
	55536
	217946
	ENSG00000164649
	ENSMUSG00000021175
	Q96GN5
	Q922M5
	NM_018719; NM_001127370; NM_001127371
	NM_146040
	NP_001120842; NP_001120843; NP_061189
	NP_666152
	Wikidata
View/Edit Human	View/Edit Mouse

Cell division cycle-associated 7-like protein is a protein that in humans is encoded by the CDCA7L gene.^[5]^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164649 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021175 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ou XM, Chen K, Shih JC (Jul 2006). "Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway". Proc Natl Acad Sci U S A. 103 (29): 10923–10928. Bibcode:2006PNAS..10310923O. doi:10.1073/pnas.0601515103. PMC 1544150. PMID 16829576.
^ "Entrez Gene: CDCA7L cell division cycle associated 7-like".

External links[edit]

Human CDCA7L genome location and CDCA7L gene details page in the UCSC Genome Browser.

Further reading[edit]

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–772. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Chen K, Ou XM, Chen G, et al. (2005). "R1, a novel repressor of the human monoamine oxidase A". J. Biol. Chem. 280 (12): 11552–11559. doi:10.1074/jbc.M410033200. PMC 2861901. PMID 15654081.
Huang A, Ho CS, Ponzielli R, et al. (2005). "Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells". Cancer Res. 65 (13): 5607–5619. doi:10.1158/0008-5472.CAN-05-0500. PMID 15994933.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–5396. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Ou XM, Chen K, Shih JC (2006). "Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1". J. Biol. Chem. 281 (30): 21512–21525. doi:10.1074/jbc.M600250200. PMID 16728402.
Maertens GN, Cherepanov P, Engelman A (2006). "Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin". J. Cell Sci. 119 (Pt 12): 2563–2571. doi:10.1242/jcs.02995. PMID 16735438. S2CID 11049784.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Bartholomeeusen K, De Rijck J, Busschots K, et al. (2007). "Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75". J. Mol. Biol. 372 (2): 407–421. doi:10.1016/j.jmb.2007.06.090. PMID 17669426.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000164649 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021175 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16829576-5] Ou XM, Chen K, Shih JC (Jul 2006). "Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway". Proc Natl Acad Sci U S A. 103 (29): 10923–10928. Bibcode:2006PNAS..10310923O. doi:10.1073/pnas.0601515103. PMC 1544150. PMID 16829576.

[entrez-6] "Entrez Gene: CDCA7L cell division cycle associated 7-like".

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