CDO may refer to:
- Cagayan de Oro, a city on Mindanao Island, Philippines
- Canyon del Oro High School, a public school in Oro Valley, Arizona, USA
- Cañada del Oro, a primary watershed channel in the valley of Tucson, Arizona, USA
- Collaboration Data Objects, a Microsoft application programming interface for data access
- Connected Data Objects, a free implementation of a distributed shared model
- Climate Data Operators, a command line suite for manipulating and analysing climate data
Command Duty Officer, is a commissioned officer not to be confused with an OOD. the most senior officer on board a US Naval vessel when the commanding officer is not present.
Chief Diversity Officer, a senior officer who strategizes, advises, and sets priorities on diversity and inclusion efforts and initiatives within corporations, universities, etc.
- Chief Data Officer, an information systems title
- Chief Dental Officer (Canada), a Canadian official who advises on oral health
- Chief Dental Officer (United Kingdom), a British government advisor for dentistry
- Chief Design Officer, a corporate design position
- Chief development officer (aka Chief business development officer), a business position
- Chief Digital Officer
- Central dense overcast, in a tropical storm
- Collateralized debt obligation, a structured finance product
- Continuous duty overnight, a regional airline crew scheduling term
- Community dial office, a telephone switching system for small communities
- Min Dong, the ISO-639 code for the spoken variation of the Chinese language
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