CEACAM8

Carcinoembryonic antigen-related cell adhesion molecule 8
PDB rendering based on 2dks.
Available structures PDB 2dks
Identifiers
Symbols	CEACAM8; CD66b; CD67; CGM6; NCA-95
External IDs	HomoloGene: 68205 GeneCards: CEACAM8 Gene
Gene Ontology Molecular function • GPI anchor binding Cellular component • extracellular space • plasma membrane • integral to plasma membrane • anchored to membrane Biological process • immune response Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1088	n/a
Ensembl	ENSG00000124469	n/a
UniProt	P31997	n/a
RefSeq (mRNA)	NM_001816	n/a
RefSeq (protein)	NP_001807	n/a
Location (UCSC)	Chr 19: 43.08 – 43.1 Mb	n/a
PubMed search	[1]	n/a

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b (Cluster of Differentiation 66b), is a human gene.

See also

• Cluster of differentiation

Further reading

• Khan WN, Frängsmyr L, Teglund S, et al. (1992). "Identification of three new genes and estimation of the size of the carcinoembryonic antigen family.". Genomics 14 (2): 384–90. doi:10.1016/S0888-7543(05)80230-7. PMID 1427854. 
• Oikawa S, Inuzuka C, Kuroki M, et al. (1991). "A specific heterotypic cell adhesion activity between members of carcinoembryonic antigen family, W272 and NCA, is mediated by N-domains.". J. Biol. Chem. 266 (13): 7995–8001. PMID 2022629. 
• Berling B, Kolbinger F, Grunert F, et al. (1990). "Cloning of a carcinoembryonic antigen gene family member expressed in leukocytes of chronic myeloid leukemia patients and bone marrow.". Cancer Res. 50 (20): 6534–9. PMID 2208113. 
• Arakawa F, Kuroki M, Misumi Y, et al. (1990). "Characterization of a cDNA clone encoding a new species of the nonspecific cross-reacting antigen (NCA), a member of the CEA gene family.". Biochem. Biophys. Res. Commun. 166 (3): 1063–71. doi:10.1016/0006-291X(90)90975-S. PMID 2306228. 
• Eades-Perner AM, Thompson J, van der Putten H, Zimmermann W (1998). "Mice transgenic for the human CGM6 gene express its product, the granulocyte marker CD66b, exclusively in granulocytes.". Blood 91 (2): 663–72. PMID 9427723. 
• Torsteinsdóttir I, Arvidson NG, Hällgren R, Håkansson L (1999). "Enhanced expression of integrins and CD66b on peripheral blood neutrophils and eosinophils in patients with rheumatoid arthritis, and the effect of glucocorticoids.". Scand. J. Immunol. 50 (4): 433–9. doi:10.1046/j.1365-3083.1999.00602.x. PMID 10520185. 
• Oikawa S, Sugiyama M, Kuroki M, et al. (2001). "Extracellular N-domain alone can mediate specific heterophilic adhesion between members of the carcinoembryonic antigen family, CEACAM6 and CEACAM8.". Biochem. Biophys. Res. Commun. 278 (3): 564–8. doi:10.1006/bbrc.2000.3858. PMID 11095950. 
• Singer BB, Scheffrahn I, Heymann R, et al. (2002). "Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes.". J. Immunol. 168 (10): 5139–46. PMID 11994468. 
• Zhao L, Xu S, Peterson C, et al. (2002). "Purification and characterization of a 95-kDa protein--carcinoembryonic antigen-related cell adhesion molecule 8--from normal human granulocytes.". J. Immunol. Methods 270 (1): 27–35. PMID 12379336. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Ramachandran P, Boontheung P, Xie Y, et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002. 

External links

• MeSH CEACAM8+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.