CENPC1

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Centromere protein C
Identifiers
Symbols CENPC ; CENP-C; CENPC1; MIF2; hcp-4
External IDs OMIM117141 MGI99700 HomoloGene1371 GeneCards: CENPC Gene
RNA expression pattern
PBB GE CENPC1 204739 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1060 12617
Ensembl ENSG00000145241 ENSMUSG00000029253
UniProt Q03188 P49452
RefSeq (mRNA) NM_001812 NM_007683
RefSeq (protein) NP_001803 NP_031709
Location (UCSC) Chr 4:
68.34 – 68.41 Mb
Chr 5:
86.01 – 86.07 Mb
PubMed search [1] [2]

Centromere protein C 1 is a protein that in humans is encoded by the CENPC1 gene.[1][2]

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.[2]

References[edit]

  1. ^ McKay S, Thomson E, Cooke H (Dec 1994). "Sequence homologies and linkage group conservation of the human and mouse Cenpc genes". Genomics 22 (1): 36–40. doi:10.1006/geno.1994.1342. PMID 7959789. 
  2. ^ a b "Entrez Gene: CENPC1 centromere protein C 1". 

Further reading[edit]