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ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Protein CENTG1 PDB 2bmj.png
PDB rendering based on 2bmj.
Available structures
PDB Ortholog search: PDBe, RCSB
External IDs OMIM605476 HomoloGene86815 GeneCards: AGAP2 Gene
RNA expression pattern
PBB GE CENTG1 206152 at tn.png
PBB GE CENTG1 215080 s at tn.png
More reference expression data
Species Human Mouse
Entrez 116986 216439
Ensembl ENSG00000135439 ENSMUSG00000025422
UniProt Q99490 Q3UHD9
RefSeq (mRNA) NM_001122772 NM_001033263
RefSeq (protein) NP_001116244 NP_001028435
Location (UCSC) Chr 12:
58.12 – 58.12 Mb
Chr 10:
127.08 – 127.09 Mb
PubMed search [1] [2]

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 is a protein that in humans is encoded by the AGAP2 gene.[1]


CENTG1 has been shown to interact with:


  1. ^ "Entrez Gene: CENTG1 centaurin, gamma 1". 
  2. ^ a b Ye K, Hurt KJ, Wu FY, Fang M, Luo HR, Hong JJ et al. (December 2000). "Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N". Cell 103 (6): 919–30. doi:10.1016/S0092-8674(00)00195-1. PMID 11136977. 
  3. ^ Rong R, Ahn JY, Huang H, Nagata E, Kalman D, Kapp JA et al. (November 2003). "PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis". Nat. Neurosci. 6 (11): 1153–61. doi:10.1038/nn1134. PMID 14528310. 

Further reading[edit]