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Centrosomal protein 120kDa
Symbols CEP120 ; CCDC100
External IDs OMIM613446 MGI2147298 HomoloGene27415 GeneCards: CEP120 Gene
Species Human Mouse
Entrez 153241 225523
Ensembl ENSG00000168944 ENSMUSG00000048799
UniProt Q8N960 Q7TSG1
RefSeq (mRNA) NM_001166226 NM_178686
RefSeq (protein) NP_001159698 NP_848801
Location (UCSC) Chr 5:
122.68 – 122.76 Mb
Chr 18:
53.68 – 53.74 Mb
PubMed search [1] [2]

Centrosomal protein of 120 kDa (Cep120), also known as coiled-coil domain-containing protein 100, is a protein that in humans is encoded by the CEP120 gene.[1][2]


This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects.[1]


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