CGP-35348

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CGP-35348
CGP-35348.svg
Systematic (IUPAC) name
3-aminopropyl(diethoxymethyl)phosphinic acid
Clinical data
Legal status
?
Identifiers
CAS number 123690-79-9 YesY
ATC code ?
PubChem CID 107699
ChemSpider 96869 N
Chemical data
Formula C8H20NO4P 
Mol. mass 225.222 g/mol
 N (what is this?)  (verify)

CGP-35348 is a compound used in scientific research which acts as an antagonist at GABAB receptors.[1][2][3]

References[edit]

  1. ^ Carter LP, Chen W, Coop A, Koek W, France CP (May 2006). "Discriminative stimulus effects of GHB and GABA(B) agonists are differentially attenuated by CGP35348". European Journal of Pharmacology 538 (1-3): 85–93. doi:10.1016/j.ejphar.2006.03.039. PMID 16647701. 
  2. ^ Nasrallah FA, Griffin JL, Balcar VJ, Rae C (August 2007). "Understanding your inhibitions: modulation of brain cortical metabolism by GABA(B) receptors". Journal of Cerebral Blood Flow and Metabolism 27 (8): 1510–20. doi:10.1038/sj.jcbfm.9600453. PMID 17293844. 
  3. ^ Koek W, Mercer SL, Coop A, France CP (September 2009). "Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348)". The Journal of Pharmacology and Experimental Therapeutics 330 (3): 876–83. doi:10.1124/jpet.109.151845. PMC 2729800. PMID 19564487.