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Cholinergic receptor, nicotinic, gamma (muscle)
External IDs OMIM100730 MGI87895 HomoloGene3810 IUPHAR: γ ChEMBL: 2613 GeneCards: CHRNG Gene
RNA expression pattern
PBB GE CHRNG 221355 at tn.png
More reference expression data
Species Human Mouse
Entrez 1146 11449
Ensembl ENSG00000196811 ENSMUSG00000026253
UniProt P07510 P04760
RefSeq (mRNA) NM_005199 NM_009604
RefSeq (protein) NP_005190 NP_033734
Location (UCSC) Chr 2:
233.4 – 233.41 Mb
Chr 1:
87.21 – 87.21 Mb
PubMed search [1] [2]

Acetylcholine receptor subunit gamma is a protein that in humans is encoded by the CHRNG gene.[1]

For background information on the acetylcholine receptor (AChR), see CHRNA1 (MIM 100690). Two forms of AChR are found in mammalian skeletal muscle cells. The mature form is predominant in innervated adult muscle and the embryonic form is present in fetal and denervated muscle. Embryonic and mature AChR differ by the replacement of the gamma subunit in the pentameric glycoprotein complex by its isoform, the epsilon subunit (MIM 100725), which is specific to the mature AChR subtype. This switch is mediated by ARIA (acetylcholine receptor-inducing activity; MIM 142445).[supplied by OMIM][1]


Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.