The station was founded in 1981 by Mountain Broadcasting, which was sold to Selkirk Communications in January 1989. Selkirk, in turn, was sold to Maclean-Hunter in September 1989, and CISQ was resold to Rogers Communications as part of the purchase. The station was relaunched with an adult contemporary format on August 29, 2003. The format later changed again in 2010.
CISQ-FM has gone through a number of frequency changes. Since the launch in 1982, the station originally began broadcasting at 104.9 FM. In 1987, CISQ moved from 104.9 to 98.3 FM and to 104.7 FM the same year. In 1988, CISQ settled to its current frequency at 107.1 FM.
On May 22, 2013, the CRTC approved Rogers' application to relocate CISW-FM Whistler from its current location to a CBC-owned tower in Whistler. This relocation will result in a decrease in the average effective radiated power (ERP) from 586 to 474 watts (directional antenna with a decrease in the maximum ERP from 1,430 to 1,000 watts) as well as an increase in the effective height of antenna above average terrain from -306.2 metres to -238.3 metres.