cI protein

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cI protein ("CI", not "CL"), also known as the lambda repressor, is the sole protein expressed in the lysogenic state of Lambda phage. cI turns off transcription at the phage's L and R promoters as well as any other invading lambda phages into the host cell. It is a transcription factor and contains the common helix-turn-helix DNA binding domain.[1]

lambda-repressor bound to DNA (PDB:1LMB)

[edit] References

  1. ^ Ptashne, Mark (February 1967). "Isolation of the λ Phage Repressor". Proc Natl Acad Sci U S A 57 (2): 306–313. PMC 335506. PMID 16591470. http://www.pnas.org/content/57/2/306.full.pdf+html. 


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