CLDN10

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Claudin 10
Identifiers
Symbols CLDN10 ; CPETRL3; OSP-L
External IDs MGI1913101 HomoloGene5076 GeneCards: CLDN10 Gene
RNA expression pattern
PBB GE CLDN10 205328 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9071 58187
Ensembl ENSG00000134873 ENSMUSG00000022132
UniProt P78369 Q9Z0S6
RefSeq (mRNA) NM_001160100 NM_001160096
RefSeq (protein) NP_001153572 NP_001153568
Location (UCSC) Chr 13:
96.09 – 96.23 Mb
Chr 14:
118.79 – 118.88 Mb
PubMed search [1] [2]

Claudin-10 is a protein that in humans is encoded by the CLDN10 gene.[1][2] It belongs to the group of claudins.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Two alternatively spliced transcript variants that encode different isoforms have been identified for this gene.[2]

References[edit]

  1. ^ Ip YC, Cheung ST, Lee YT, Ho JC, Fan ST (Nov 2007). "Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells". Mol Cancer Ther 6 (11): 2858–67. doi:10.1158/1535-7163.MCT-07-0453. PMID 18025272. 
  2. ^ a b "Entrez Gene: CLDN10 claudin 10". 

Further reading[edit]