CLDN17

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Claudin 17
Identifiers
Symbols CLDN17 ; MGC126552; MGC126554
External IDs MGI2652030 HomoloGene8116 GeneCards: CLDN17 Gene
RNA expression pattern
PBB GE CLDN17 221328 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 26285 239931
Ensembl ENSG00000156282 ENSMUSG00000055811
UniProt P56750 Q8BXA6
RefSeq (mRNA) NM_012131 NM_181490
RefSeq (protein) NP_036263 NP_852467
Location (UCSC) Chr 21:
31.54 – 31.54 Mb
Chr 16:
88.51 – 88.51 Mb
PubMed search [1] [2]

Claudin-17 is a protein that in humans is encoded by the CLDN17 gene.[1][2] It belongs to the group of claudins. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.[3]


References[edit]

  1. ^ Katoh M, Katoh M (May 2003). "CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family". Int J Mol Med 11 (6): 683–9. PMID 12736707. 
  2. ^ "Entrez Gene: CLDN17 claudin 17". 
  3. ^ Krug SM, Günzel D, Conrad MP, Rosenthal R, Fromm A, Amasheh S, Schulzke JD, Fromm M (2012). "Claudin-17 forms tight junction channels with distinct anion selectivity". Cell Mol Life Sci 69 (16): 2765–78. doi:10.1007/s00018-012-0949-x. PMID 22402829. 

Further reading[edit]