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Claudin 17
Symbols CLDN17 ; MGC126552; MGC126554
External IDs MGI2652030 HomoloGene8116 GeneCards: CLDN17 Gene
RNA expression pattern
PBB GE CLDN17 221328 at tn.png
More reference expression data
Species Human Mouse
Entrez 26285 239931
Ensembl ENSG00000156282 ENSMUSG00000055811
UniProt P56750 Q8BXA6
RefSeq (mRNA) NM_012131 NM_181490
RefSeq (protein) NP_036263 NP_852467
Location (UCSC) Chr 21:
31.54 – 31.54 Mb
Chr 16:
88.51 – 88.51 Mb
PubMed search [1] [2]

Claudin-17 is a protein that in humans is encoded by the CLDN17 gene.[1][2] It belongs to the group of claudins. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.[3]


  1. ^ Katoh M, Katoh M (May 2003). "CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family". Int J Mol Med 11 (6): 683–9. doi:10.3892/ijmm.11.6.683. PMID 12736707. 
  2. ^ "Entrez Gene: CLDN17 claudin 17". 
  3. ^ Krug SM, Günzel D, Conrad MP, Rosenthal R, Fromm A, Amasheh S, Schulzke JD, Fromm M (2012). "Claudin-17 forms tight junction channels with distinct anion selectivity". Cell Mol Life Sci 69 (16): 2765–78. doi:10.1007/s00018-012-0949-x. PMID 22402829. 

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