CLDN4

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Claudin 4
Identifiers
Symbols CLDN4 ; CPE-R; CPER; CPETR; CPETR1; WBSCR8; hCPE-R
External IDs OMIM602909 MGI1313314 HomoloGene1000 GeneCards: CLDN4 Gene
RNA expression pattern
PBB GE CLDN4 201428 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1364 12740
Ensembl ENSG00000189143 ENSMUSG00000047501
UniProt O14493 O35054
RefSeq (mRNA) NM_001305 NM_009903
RefSeq (protein) NP_001296 NP_034033
Location (UCSC) Chr 7:
73.21 – 73.25 Mb
Chr 5:
134.95 – 134.95 Mb
PubMed search [1] [2]

Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins.

This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.[1]

References[edit]


Further reading[edit]