CLDN7

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Claudin 7
Identifiers
Symbols CLDN7 ; CEPTRL2; CLDN-7; CPETRL2; Hs.84359; claudin-1
External IDs OMIM609131 MGI1859285 HomoloGene9649 GeneCards: CLDN7 Gene
RNA expression pattern
PBB GE CLDN7 202790 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1366 53624
Ensembl ENSG00000181885 ENSMUSG00000018569
UniProt O95471 Q9Z261
RefSeq (mRNA) NM_001185022 NM_001193619
RefSeq (protein) NP_001171951 NP_001180548
Location (UCSC) Chr 17:
7.16 – 7.17 Mb
Chr 11:
69.96 – 69.97 Mb
PubMed search [1] [2]

Claudin-7 is a protein that in humans is encoded by the CLDN7 gene.[1][2] It belongs to the group of claudins.

Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells (Zheng et al., 2003).[supplied by OMIM][2]

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