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C-type lectin domain family 2, member B
Symbols CLEC2B ; AICL; CLECSF2; HP10085; IFNRG1
External IDs OMIM603242 HomoloGene68443 GeneCards: CLEC2B Gene
RNA expression pattern
PBB GE CLEC2B 209732 at tn.png
More reference expression data
Species Human Mouse
Entrez 9976 n/a
Ensembl ENSG00000110852 n/a
UniProt Q92478 n/a
RefSeq (mRNA) NM_005127 n/a
RefSeq (protein) NP_005118 n/a
Location (UCSC) Chr 12:
10.01 – 10.02 Mb
PubMed search [1] n/a

C-type lectin domain family 2 member B is a protein that in humans is encoded by the CLEC2B gene.[1][2]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.[2]


  1. ^ Hamann J, Montgomery KT, Lau S, Kucherlapati R, van Lier RA (Mar 1997). "AICL: a new activation-induced antigen encoded by the human NK gene complex". Immunogenetics 45 (5): 295–300. doi:10.1007/s002510050208. PMID 9038101. 
  2. ^ a b "Entrez Gene: CLEC2B C-type lectin domain family 2, member B". 

Further reading[edit]