CLEC2D

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C-type lectin domain family 2, member D
Identifiers
Symbols CLEC2D ; CLAX; LLT1; OCIL
External IDs OMIM605659 MGI2136934 HomoloGene128584 GeneCards: CLEC2D Gene
Orthologs
Species Human Mouse
Entrez 29121 70809
Ensembl ENSG00000213443 ENSMUSG00000000248
UniProt Q9UHP7 Q9D676
RefSeq (mRNA) NM_001004419 NM_001168223
RefSeq (protein) NP_001004419 NP_001161695
Location (UCSC) Chr 12:
9.81 – 9.85 Mb
Chr 6:
128.93 – 128.98 Mb
PubMed search [1] [2]

C-type lectin domain family 2 member D is a protein that in humans is encoded by the CLEC2D gene.[1]

This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified, but the full-length nature of every transcript has not been defined.[1] CLEC2D encodes the gene for the Lectin Like Transcript-1 (LLT1) protein which is a functional ligand for the human NKR-P1A receptor, encoded by the KLRB1 gene.

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