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CAP-GLY domain containing linker protein 1
Protein CLIP1 PDB 2cp5.png
PDB rendering based on 2cp5.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols CLIP1 ; CLIP; CLIP-170; CLIP170; CYLN1; RSN
External IDs OMIM179838 MGI1928401 HomoloGene74455 GeneCards: CLIP1 Gene
RNA expression pattern
PBB GE CLIP1 201975 at tn.png
PBB GE CLIP1 210716 s at tn.png
More reference expression data
Species Human Mouse
Entrez 6249 56430
Ensembl ENSG00000130779 ENSMUSG00000049550
UniProt P30622 Q922J3
RefSeq (mRNA) NM_001247997 NM_001291229
RefSeq (protein) NP_001234926 NP_001278158
Location (UCSC) Chr 12:
122.76 – 122.91 Mb
Chr 5:
123.58 – 123.68 Mb
PubMed search [1] [2]

CAP-GLY domain containing linker protein 1, also known as CLIP1, is a protein which in humans is encoded by the CLIP1 gene.[1]


CLIP1 has been shown to interact with IQGAP1,[2] Mammalian target of rapamycin[3] and PAFAH1B1.[4]


  1. ^ "Entrez Gene: CLIP1 CAP-GLY domain containing linker protein 1". 
  2. ^ Fukata, Masaki; Watanabe Takashi; Noritake Jun; Nakagawa Masato; Yamaga Masaki; Kuroda Shinya; Matsuura Yoshiharu; Iwamatsu Akihiro; Perez Franck; Kaibuchi Kozo (Jun 2002). "Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170". Cell (United States) 109 (7): 873–85. doi:10.1016/S0092-8674(02)00800-0. ISSN 0092-8674. PMID 12110184. 
  3. ^ Choi, Jae H; Bertram Paula G; Drenan Ryan; Carvalho John; Zhou Heather H; Zheng X F Steven (Oct 2002). "The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase". EMBO Rep. (England) 3 (10): 988–94. doi:10.1093/embo-reports/kvf197. ISSN 1469-221X. PMC 1307618. PMID 12231510. 
  4. ^ Coquelle, Frédéric M; Caspi Michal, Cordelières Fabrice P, Dompierre Jim P, Dujardin Denis L, Koifman Cynthia, Martin Patrick, Hoogenraad Casper C, Akhmanova Anna, Galjart Niels, De Mey Jan R, Reiner Orly (May 2002). "LIS1, CLIP-170's Key to the Dynein/Dynactin Pathway". Mol. Cell. Biol. (United States) 22 (9): 3089–102. doi:10.1128/MCB.22.9.3089-3102.2002. ISSN 0270-7306. PMC 133759. PMID 11940666. 

Further reading[edit]