CNTNAP4

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Contactin associated protein-like 4
Identifiers
Symbols CNTNAP4 ; CASPR4
External IDs OMIM610518 MGI2183572 HomoloGene24912 GeneCards: CNTNAP4 Gene
Orthologs
Species Human Mouse
Entrez 85445 170571
Ensembl ENSG00000152910 ENSMUSG00000031772
UniProt Q9C0A0 Q99P47
RefSeq (mRNA) NM_033401 NM_130457
RefSeq (protein) NP_207837 NP_569724
Location (UCSC) Chr 16:
76.31 – 76.59 Mb
Chr 8:
112.57 – 112.88 Mb
PubMed search [1] [2]

Contactin-associated protein-like 4 is a protein that in humans is encoded by the CNTNAP4 gene.[1][2]

This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. Alternative splicing results in two transcript variants encoding different isoforms.[2]

References[edit]

  1. ^ Spiegel I, Salomon D, Erne B, Schaeren-Wiemers N, Peles E (Jul 2002). "Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains". Mol Cell Neurosci 20 (2): 283–97. doi:10.1006/mcne.2002.1110. PMID 12093160. 
  2. ^ a b "Entrez Gene: CNTNAP4 contactin associated protein-like 4". 

Further reading[edit]