CNTRL

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For the Electronic Dance Music educational initiative, see CNTRL: Beyond EDM.
Centriolin
Identifiers
Symbols CNTRL ; CEP1; CEP110; FAN; bA165P4.1
External IDs OMIM605496 HomoloGene38260 GeneCards: CNTRL Gene
RNA expression pattern
PBB GE CEP110 205642 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 11064 26920
Ensembl ENSG00000119397 ENSMUSG00000057110
UniProt Q7Z7A1 E9Q9E7
RefSeq (mRNA) NM_007018 NM_012018
RefSeq (protein) NP_008949 NP_036148
Location (UCSC) Chr 9:
123.84 – 123.94 Mb
Chr 2:
35.11 – 35.18 Mb
PubMed search [1] [2]

Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110.[1][2]

This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centriolin.[2]

References[edit]

  1. ^ Guasch G, Mack GJ, Popovici C, Dastugue N, Birnbaum D, Rattner JB, Pebusque MJ (Mar 2000). "FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)". Blood 95 (5): 1788–96. PMID 10688839. 
  2. ^ a b "Entrez Gene: CEP110 centrosomal protein 110kDa". 

Further reading[edit]