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For the Electronic Dance Music educational initiative, see CNTRL: Beyond EDM.
Symbols CNTRL ; CEP1; CEP110; FAN; bA165P4.1
External IDs OMIM605496 HomoloGene38260 GeneCards: CNTRL Gene
RNA expression pattern
PBB GE CEP110 205642 at tn.png
More reference expression data
Species Human Mouse
Entrez 11064 26920
Ensembl ENSG00000119397 ENSMUSG00000057110
UniProt Q7Z7A1 E9Q9E7
RefSeq (mRNA) NM_007018 NM_012018
RefSeq (protein) NP_008949 NP_036148
Location (UCSC) Chr 9:
123.84 – 123.94 Mb
Chr 2:
35.11 – 35.18 Mb
PubMed search [1] [2]

Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110.[1][2]

This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centriolin.[2]


  1. ^ Guasch G, Mack GJ, Popovici C, Dastugue N, Birnbaum D, Rattner JB, Pebusque MJ (Mar 2000). "FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)". Blood 95 (5): 1788–96. PMID 10688839. 
  2. ^ a b "Entrez Gene: CEP110 centrosomal protein 110kDa". 

Further reading[edit]