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Coatomer protein complex, subunit gamma 2
Symbols COPG2 ; 2-COP; gamma-2-COP
External IDs OMIM604355 HomoloGene56292 GeneCards: COPG2 Gene
Species Human Mouse
Entrez 26958 54160
Ensembl ENSG00000158623 ENSMUSG00000025607
UniProt Q9UBF2 Q9QXK3
RefSeq (mRNA) NM_001290033 NM_017478
RefSeq (protein) NP_001276962 NP_059506
Location (UCSC) Chr 7:
130.15 – 130.35 Mb
Chr 6:
30.75 – 30.9 Mb
PubMed search [1] [2]

Coatomer subunit gamma-2 is a protein that in humans is encoded by the COPG2 gene.[1][2][3]


COPG2 has been shown to interact with Dopamine receptor D1[4] and COPB1.[5][6]


  1. ^ Blagitko N, Schulz U, Schinzel AA, Ropers HH, Kalscheuer VM (Jan 2000). "gamma2-COP, a novel imprinted gene on chromosome 7q32, defines a new imprinting cluster in the human genome". Hum Mol Genet 8 (13): 2387–96. doi:10.1093/hmg/8.13.2387. PMID 10556286. 
  2. ^ Yamasaki K, Hayashida S, Miura K, Masuzaki H, Ishimaru T, Niikawa N et al. (Nov 2000). "The novel gene, gamma2-COP (COPG2), in the 7q32 imprinted domain escapes genomic imprinting". Genomics 68 (3): 330–5. doi:10.1006/geno.2000.6265. PMID 10995575. 
  3. ^ "Entrez Gene: COPG2 coatomer protein complex, subunit gamma 2". 
  4. ^ Bermak JC, Li M, Bullock C, Weingarten P, Zhou QY (Feb 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. 81 (2): 77–85. doi:10.1078/0171-9335-00222. PMID 11893085. 
  5. ^ Takatsu H, Futatsumori M, Yoshino K, Yoshida Y, Shin HW, Nakayama K (Jun 2001). "Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system". Biochem. Biophys. Res. Commun. 284 (4): 1083–9. doi:10.1006/bbrc.2001.5081. PMID 11409905. 
  6. ^ Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (2000). "Identification and characterization of novel isoforms of COP I subunits.". J Biochem 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392. 

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