COQ2

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Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Identifiers
Symbols COQ2 ; CL640; COQ10D1; MSA1
External IDs OMIM609825 MGI1919133 HomoloGene69192 GeneCards: COQ2 Gene
EC number 2.5.1.39
RNA expression pattern
PBB GE COQ2 213379 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 27235 71883
Ensembl ENSG00000173085 ENSMUSG00000029319
UniProt Q96H96 Q66JT7
RefSeq (mRNA) NM_015697 NM_027978
RefSeq (protein) NP_056512 NP_082254
Location (UCSC) Chr 4:
84.18 – 84.21 Mb
Chr 5:
100.65 – 100.68 Mb
PubMed search [1] [2]

Para-hydroxybenzoate--polyprenyltransferase, mitochondrial is an enzyme that in humans is encoded by the COQ2 gene.[1][2]

CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004).[supplied by OMIM][2]

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