CPNE4

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Copine IV
Identifiers
Symbols CPNE4 ; COPN4; CPN4
External IDs OMIM604208 MGI1921270 HomoloGene26078 GeneCards: CPNE4 Gene
RNA expression pattern
PBB GE CPNE4 gnf1h09017 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 131034 74020
Ensembl ENSG00000196353 ENSMUSG00000032564
UniProt Q96A23 Q8BLR2
RefSeq (mRNA) NM_001289112 NM_028719
RefSeq (protein) NP_001276041 NP_082995
Location (UCSC) Chr 3:
131.25 – 132 Mb
Chr 9:
104.55 – 105.03 Mb
PubMed search [1] [2]

Copine-4 is a protein that in humans is encoded by the CPNE4 gene.[1][2][3]

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.[3]

References[edit]

  1. ^ Creutz CE, Tomsig JL, Snyder SL, Gautier MC, Skouri F, Beisson J, Cohen J (Feb 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans". J Biol Chem 273 (3): 1393–402. doi:10.1074/jbc.273.3.1393. PMID 9430674. 
  2. ^ Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8". Biochem Biophys Res Commun 303 (3): 842–7. doi:10.1016/S0006-291X(03)00445-5. PMID 12670487. 
  3. ^ a b "Entrez Gene: CPNE4 copine IV". 

Further reading[edit]