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Copine VI (neuronal)
Symbols CPNE6 ; N-COPINE
External IDs OMIM605688 MGI1334445 HomoloGene81815 GeneCards: CPNE6 Gene
RNA expression pattern
PBB GE CPNE6 210408 s at tn.png
PBB GE CPNE6 215700 x at tn.png
More reference expression data
Species Human Mouse
Entrez 9362 12891
Ensembl ENSG00000100884 ENSMUSG00000022212
UniProt O95741 Q9Z140
RefSeq (mRNA) NM_001280558 NM_001136057
RefSeq (protein) NP_001267487 NP_001129529
Location (UCSC) Chr 14:
24.54 – 24.55 Mb
Chr 14:
55.51 – 55.52 Mb
PubMed search [1] [2]

Copine-6 is a protein that in humans is encoded by the CPNE6 gene.[1][2]

This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.[2]


  1. ^ Nakayama T, Yaoi T, Yasui M, Kuwajima G (Jul 1998). "N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression". FEBS Lett 428 (1–2): 80–4. doi:10.1016/S0014-5793(98)00497-9. PMID 9645480. 
  2. ^ a b "Entrez Gene: CPNE6 copine VI (neuronal)". 

Further reading[edit]