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Casein kinase 1, delta
Protein CSNK1D PDB 1cki.png
PDB rendering based on 1cki.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols CSNK1D ; ASPS; CKIdelta; FASPS2; HCKID
External IDs OMIM600864 MGI1355272 HomoloGene74841 IUPHAR: 1997 ChEMBL: 2828 GeneCards: CSNK1D Gene
EC number,
RNA expression pattern
PBB GE CSNK1D 207945 s at tn.png
PBB GE CSNK1D 208774 at tn.png
More reference expression data
Species Human Mouse
Entrez 1453 104318
Ensembl ENSG00000141551 ENSMUSG00000025162
UniProt P48730 Q9DC28
RefSeq (mRNA) NM_001893 NM_027874
RefSeq (protein) NP_001884 NP_082150
Location (UCSC) Chr 17:
80.2 – 80.23 Mb
Chr 11:
120.96 – 120.99 Mb
PubMed search [1] [2]

The CSNK1D gene encodes the casein kinase I isoform delta enzyme in humans.[1]

This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene.[2]


CSNK1D has been shown to interact with Gap junction protein, alpha 1.[3]


  1. ^ Fish KJ, Cegielska A, Getman ME, Landes GM, Virshup DM (Jul 1995). "Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family". J Biol Chem 270 (25): 14875–83. doi:10.1074/jbc.270.25.14875. PMID 7797465. 
  2. ^ "Entrez Gene: CSNK1D casein kinase 1, delta". 
  3. ^ Cooper, Cynthia D; Lampe Paul D (Nov 2002). "Casein kinase 1 regulates connexin-43 gap junction assembly". J. Biol. Chem. (United States) 277 (47): 44962–8. doi:10.1074/jbc.M209427200. ISSN 0021-9258. PMID 12270943. 

Further reading[edit]