CTTNBP2

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Cortactin binding protein 2
Identifiers
Symbols CTTNBP2 ; C7orf8; CORTBP2; Orf4
External IDs OMIM609772 MGI1353467 HomoloGene14125 GeneCards: CTTNBP2 Gene
RNA expression pattern
PBB GE CTTNBP2 gnf1h06054 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 83992 30785
Ensembl ENSG00000077063 ENSMUSG00000000416
UniProt Q8WZ74 B9EJA2
RefSeq (mRNA) NM_033427 NM_080285
RefSeq (protein) NP_219499 NP_525024
Location (UCSC) Chr 7:
117.35 – 117.51 Mb
Chr 6:
18.37 – 18.51 Mb
PubMed search [1] [2]

Cortactin-binding protein 2 is a protein that in humans is encoded by the CTTNBP2 gene.[1][2]

This gene encodes a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton.[2]

Interactions[edit]

CTTNBP2 has been shown to interact with RP6-213H19.1,[3] STRN,[3] STRN3,[3] MOBKL3[3] and PPP2CA.[3]

References[edit]

  1. ^ Cheung J, Petek E, Nakabayashi K, Tsui LC, Vincent JB, Scherer SW (Nov 2001). "Identification of the human cortactin-binding protein-2 gene from the autism candidate region at 7q31". Genomics 78 (1-2): 7–11. doi:10.1006/geno.2001.6651. PMID 11707066. 
  2. ^ a b "Entrez Gene: CTTNBP2 cortactin binding protein 2". 
  3. ^ a b c d e Goudreault, Marilyn; D'Ambrosio Lisa M, Kean Michelle J, Mullin Michael J, Larsen Brett G, Sanchez Amy, Chaudhry Sidharth, Chen Ginny I, Sicheri Frank, Nesvizhskii Alexey I, Aebersold Ruedi, Raught Brian, Gingras Anne-Claude (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Mol. Cell Proteomics (United States) 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753. 

Further reading[edit]