CYP2J2

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Cytochrome P450, family 2, subfamily J, polypeptide 2
Identifiers
Symbols CYP2J2 ; CPJ2
External IDs OMIM601258 MGI1270148 HomoloGene128043 ChEMBL: 3491 GeneCards: CYP2J2 Gene
EC number 1.14.14.1
RNA expression pattern
PBB GE CYP2J2 205073 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1573 13110
Ensembl ENSG00000134716 ENSMUSG00000052914
UniProt P51589 O54750
RefSeq (mRNA) NM_000775 NM_010008
RefSeq (protein) NP_000766 NP_034138
Location (UCSC) Chr 1:
60.36 – 60.39 Mb
Chr 4:
96.52 – 96.55 Mb
PubMed search [1] [2]

Cytochrome P450 2J2 is a protein that in humans is encoded by the CYP2J2 gene.[1][2]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.[2]

References[edit]

  1. ^ Ma J, Ramachandran S, Fiedorek FT Jr, Zeldin DC (Jun 1998). "Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4". Genomics 49 (1): 152–5. doi:10.1006/geno.1998.5235. PMID 9570962. 
  2. ^ a b "Entrez Gene: CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2". 

Further reading[edit]