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Cytochrome P450, family 4, subfamily A, polypeptide 22
Symbol CYP4A22
External IDs OMIM615341 MGI88612 HomoloGene134044 GeneCards: CYP4A22 Gene
EC number
Species Human Mouse
Entrez 284541 13118
Ensembl ENSG00000162365 ENSMUSG00000078597
UniProt Q5TCH4 B0G0Y2
RefSeq (mRNA) NM_001010969 NM_172306
RefSeq (protein) NP_001010969 NP_758510
Location (UCSC) Chr 1:
47.39 – 47.41 Mb
Chr 4:
115.41 – 115.44 Mb
PubMed search [1] [2]

CYP4A22 (cytochrome P450, family 4, subfamily A, polypeptide 22) also known as fatty acid omega-hydroxylase is a protein which in humans is encoded by the CYP4A22 gene.[1]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.[2]


  1. ^ Hiratsuka M, Nozawa H, Katsumoto Y, Moteki T, Sasaki T, Konno Y, Mizugaki M (July 2006). "Genetic polymorphisms and haplotype structures of the CYP4A22 gene in a Japanese population". Mutat. Res. 599 (1–2): 98–104. doi:10.1016/j.mrfmmm.2006.02.008. PMID 16806293. 
  2. ^ "Entrez Gene: CYP4A22". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.