CYP4F11

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Cytochrome P450, family 4, subfamily F, polypeptide 11
Identifiers
Symbols CYP4F11 ; CYPIVF11
External IDs OMIM611517 MGI3645508 HomoloGene117991 GeneCards: CYP4F11 Gene
EC number 1.14.14.1
Orthologs
Species Human Mouse
Entrez 57834 631304
Ensembl ENSG00000171903 ENSMUSG00000090700
UniProt Q9HBI6 n/a
RefSeq (mRNA) NM_001128932 NM_001101588
RefSeq (protein) NP_001122404 NP_001095058
Location (UCSC) Chr 19:
16.02 – 16.05 Mb
Chr 17:
32.66 – 32.68 Mb
PubMed search [1] [2]

CYP4F11 (cytochrome P450, family 4, subfamily F, polypeptide 11) is a protein that in humans is encoded by the CYP4F11 gene.[1]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[2]

References[edit]

  1. ^ Cui X, Nelson DR, Strobel HW (September 2000). "A novel human cytochrome P450 4F isoform (CYP4F11): cDNA cloning, expression, and genomic structural characterization". Genomics 68 (2): 161–6. doi:10.1006/geno.2000.6276. PMID 10964514. 
  2. ^ "Entrez Gene: CYP4F11". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.