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Cytochrome P450, family 4, subfamily X, polypeptide 1
Symbols CYP4X1 ; CYPIVX1
External IDs OMIM614999 MGI1932403 HomoloGene75853 IUPHAR: 1351 GeneCards: CYP4X1 Gene
EC number
Species Human Mouse
Entrez 260293 81906
Ensembl ENSG00000186377 ENSMUSG00000047155
UniProt Q8N118 Q6A152
RefSeq (mRNA) NM_178033 NM_001003947
RefSeq (protein) NP_828847 NP_001003947
Location (UCSC) Chr 1:
47.43 – 47.52 Mb
Chr 4:
115.11 – 115.13 Mb
PubMed search [1] [2]

CYP4X1 (cytochrome P450, family 4, subfamily X, polypeptide 1) is a protein which in humans is encoded by the CYP4X1 gene.[1]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.[2]


  1. ^ Bylund J; Zhang C; Harder DR (August 2002). "Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain". Biochem. Biophys. Res. Commun. 296 (3): 677–84. doi:10.1016/S0006-291X(02)00918-X. PMID 12176035. 
  2. ^ "Entrez Gene: CYP4X1". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.