|Classification and external resources|
|ICD-9||540.0 540.9 541|
The condition is usually caused by gram-positive enteric commensal bacteria of the gut (gut flora). Clostridium difficile is a species of gram-positive bacteria that commonly causes severe diarrhea and other intestinal diseases when competing bacteria are wiped out by antibiotics.
Signs and symptoms
Inflammation can spread to other parts of the gut in patients with caecitis.
The condition can also cause the cecum to become distended and can cut off its blood supply. This and other factors can result in necrosis and perforation of the bowel, which can cause peritonitis and sepsis. The mortality rate for caecitis can be as high as 40 to 50%, mostly because it is frequently associated with bowel perforation. Caecitis is diagnosed with a radiograph CT scan showing thickening of the cecum and "fat stranding".
Successful treatment hinges on:
- Early diagnosis provided by a high index of suspicion and the use of CT scanning
- Nonoperative treatment for uncomplicated cases, and
- elective right hemicolectomy to prevent recurrence.
"...The authors have found nonoperative treatment highly effective in patients who do not manifest signs of peritonitis, perforation, gastrointestinal hemorrhage, or clinical deterioration. Recurrent typhlitis was frequent after conservative therapy (recurrence rate, 67 percent), however."
- Definition at thefreedictionary.com
- Keidan, RD; Fanning, Gatenby, Weese (Mar 1989). "Recurrent typhlitis. A disease resulting from aggressive chemotherapy". Dis Colon Rectum. 32(3): 206–9. doi:10.1007/BF02554529. PMID 2920627.
- Stoehr TM and Koslin DB. 2004. Typhlitis Imaging. emedicine.com.
- L Boggio1, R Pooley2, S I Roth2 and J N Winter1 Typhlitis complicating autologous blood stem cell transplantation for breast cancer NATURE, February 2000, Volume 25, Number 3, Pages 321-326