Caf1 capsule antigen

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PDB 1p5u EBI.jpg
x-ray structure of the ternary caf1m:caf1:caf1 chaperone:subunit:subunit complex
Symbol Antig_Caf1
Pfam PF09255
InterPro IPR015335
SCOP 1p5v

In molecular biology, Caf1 capsule antigen proteins are a family of the F1 capsule antigens Caf1 synthesised by Yersinia bacteria. They adopt a structure consisting of a seven strands arranged in two beta-sheets, in a Greek-key topology, and mediate targeting of the bacterium to sites of infection.[1]


  1. ^ Zavialov AV, Berglund J, Pudney AF, Fooks LJ, Ibrahim TM, MacIntyre S, Knight SD (May 2003). "Structure and biogenesis of the capsular F1 antigen from Yersinia pestis: preserved folding energy drives fiber formation". Cell 113 (5): 587–96. doi:10.1016/S0092-8674(03)00351-9. PMID 12787500. 

This article incorporates text from the public domain Pfam and InterPro IPR015335