|Metropolitan area of the Californias|
|Country|| United States
- El Centro
- Santa Isabel
|Population (2010 est.)|
|MSA/CSA = 2010, Urban = 2000|
|Time zone||PST (UTC-8)|
Calexico–Mexicali is an international metropolitan area in eastern California and Baja California with its center between the sister cities of Calexico and Mexicali. The metropolitan area lies in the south Salton Valley where the valley is divided into the Imperial Valley and Mexicali Valley.
Calexico–Mexicali is one of two international metropolitan regions on the California-Baja California Border.